Ki Summary

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Target

5-hydroxytryptamine receptor 1D

Ligand

BDBM50024204

Substrate/Competitor

n/a

1700±n/a nM

Comments

PDSP_1206

Citation

Hamblin, MW; Metcalf, MA Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor. Mol Pharmacol40:143-8 (1991) [PubMed]

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5-hydroxytryptamine receptor 1D

Name:

5-hydroxytryptamine receptor 1D

Synonyms:

Type:

G Protein-Coupled Receptor (GPCR)

Mol. Mass.:

41920.63

Organism:

Homo sapiens (Human)

Description:

Receptor binding assays were performed using human clone stably expressed in CHO cells.

Residue:

377

Sequence:

MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL
TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT
CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK
AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT
TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT
KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN
EEFRQAFQKIVPFRKAS

BDBM50024204

n/a

Name

BDBM50024204

Synonyms:

1H-imidazo[4,5-c]pyridine derivative | 2N-[4,7-dimethyl-(6aR,9S,10aR)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl]-2-dimethylaminosulfonamide | 4,7-dimethyl-(6aR,9S,10aR)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-amino-N,N-dimethyl sulfonamide | 4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-amine-sulfonamide | 9-N,N-dimethylsulfamide-4,7-dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline | CHEMBL12314 | ChEMBL_10959 | MESULERGINE | N'-4,7-Dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-N'-,N'-dimethyl-sulphonediamine

Type

Small organic molecule

Emp. Form.

C18H26N4O2S

Mol. Mass.

362.49

SMILES

CN(C)S(=O)(=O)N[C@H]1C[C@H]2[C@@H](Cc3cn(C)c4cccc2c34)N(C)C1

Structure