| Reaction Details |
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 | Report a problem with these data |
| Target | Dopamine receptor D4 |
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| Ligand | BDBM50007567 |
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| Substrate/Competitor | n/a |
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| Ki | 13.5±n/a nM |
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| Comments | PDSP_3957 |
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| Citation |  Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature350:610-4 (1991) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Dopamine receptor D4 |
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| Name: | Dopamine receptor D4 |
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| Synonyms: | DOPAMINE D2 Long | DOPAMINE D4 | DRD2 | Dopamine receptor D4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43731.97 |
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| Organism: | CANINE |
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| Description: | Q589Y6 |
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| Residue: | 421 |
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| Sequence: | AGDADGLLAGRGPGAGTPGTPGAAAALAGGVLLIGAVLAGNALVCASVAAERALQTPTNY
FIVSLAAADLLLALLVLPLFVYSEVQGGVWLFSPGLCDALMAMDVMLCTASIFNLCAISV
DRFVAVAVPLSYNRQGGGGRQLLLIGATWLLSAAVAAPVLCGLNDARGRDPAVCRLEDRD
YVVYSSVCSFFLPCPLMLLLYWATFRGLRRWEAARRAKLHGRTPRRPSGPGPPPPDGSPD
GTPGPPPPDGSPDGTSDGTPGPPPPDGSPDGTPGPPPPDGSPDDNPRPPPPDSSPGPPPP
EVTPDDTPDATPRPLPPAADAAAPPPADPAEPPRQPRKRRRAKITGRERKAMRVLPVVVG
AFLLCWTPFFVVHITRALCPACPVPPRLVSAVTWLGYVNSALNPLIYTVFNAEFRAVFRK
A
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| BDBM50007567 |
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| n/a |
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| Name | BDBM50007567 |
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| Synonyms: | 1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine | CHEMBL64875 | OCTOCLOTHEPIN-R |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21ClN2S |
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| Mol. Mass. | 344.901 |
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| SMILES | CN1CCN(CC1)[C@@H]1Cc2ccccc2Sc2ccc(Cl)cc12 |
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| Structure | 
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