| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dopamine receptor D4 |
|---|
| Ligand | BDBM50007568 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 1.5±n/a nM |
|---|
| Comments | PDSP_3956 |
|---|
| Citation |  Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature350:610-4 (1991) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Dopamine receptor D4 |
|---|
| Name: | Dopamine receptor D4 |
|---|
| Synonyms: | DOPAMINE D2 Long | DOPAMINE D4 | DRD2 | Dopamine receptor D4 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 43731.97 |
|---|
| Organism: | CANINE |
|---|
| Description: | Q589Y6 |
|---|
| Residue: | 421 |
|---|
| Sequence: | AGDADGLLAGRGPGAGTPGTPGAAAALAGGVLLIGAVLAGNALVCASVAAERALQTPTNY
FIVSLAAADLLLALLVLPLFVYSEVQGGVWLFSPGLCDALMAMDVMLCTASIFNLCAISV
DRFVAVAVPLSYNRQGGGGRQLLLIGATWLLSAAVAAPVLCGLNDARGRDPAVCRLEDRD
YVVYSSVCSFFLPCPLMLLLYWATFRGLRRWEAARRAKLHGRTPRRPSGPGPPPPDGSPD
GTPGPPPPDGSPDGTSDGTPGPPPPDGSPDGTPGPPPPDGSPDDNPRPPPPDSSPGPPPP
EVTPDDTPDATPRPLPPAADAAAPPPADPAEPPRQPRKRRRAKITGRERKAMRVLPVVVG
AFLLCWTPFFVVHITRALCPACPVPPRLVSAVTWLGYVNSALNPLIYTVFNAEFRAVFRK
A
|
|
|
|---|
| BDBM50007568 |
|---|
| n/a |
|---|
| Name | BDBM50007568 |
|---|
| Synonyms: | 1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine | 1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine | CHEMBL303313 | OCTOCLOTHEPIN-S |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H21ClN2S |
|---|
| Mol. Mass. | 344.901 |
|---|
| SMILES | CN1CCN(CC1)[C@H]1Cc2ccccc2Sc2ccc(Cl)cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
