| Reaction Details |
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 | Report a problem with these data |
| Target | Dopamine receptor D4 |
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| Ligand | BDBM84637 |
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| Substrate/Competitor | n/a |
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| Ki | 4.8±n/a nM |
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| Comments | PDSP_1576 |
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| Citation |  Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature350:610-4 (1991) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Dopamine receptor D4 |
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| Name: | Dopamine receptor D4 |
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| Synonyms: | DOPAMINE D2 Long | DOPAMINE D4 | DRD2 | Dopamine receptor D4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43731.97 |
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| Organism: | CANINE |
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| Description: | Q589Y6 |
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| Residue: | 421 |
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| Sequence: | AGDADGLLAGRGPGAGTPGTPGAAAALAGGVLLIGAVLAGNALVCASVAAERALQTPTNY
FIVSLAAADLLLALLVLPLFVYSEVQGGVWLFSPGLCDALMAMDVMLCTASIFNLCAISV
DRFVAVAVPLSYNRQGGGGRQLLLIGATWLLSAAVAAPVLCGLNDARGRDPAVCRLEDRD
YVVYSSVCSFFLPCPLMLLLYWATFRGLRRWEAARRAKLHGRTPRRPSGPGPPPPDGSPD
GTPGPPPPDGSPDGTSDGTPGPPPPDGSPDGTPGPPPPDGSPDDNPRPPPPDSSPGPPPP
EVTPDDTPDATPRPLPPAADAAAPPPADPAEPPRQPRKRRRAKITGRERKAMRVLPVVVG
AFLLCWTPFFVVHITRALCPACPVPPRLVSAVTWLGYVNSALNPLIYTVFNAEFRAVFRK
A
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| BDBM84637 |
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| n/a |
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| Name | BDBM84637 |
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| Synonyms: | CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPIROLE | Quinpirole,(-) | US9359372, Quinpirole |
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| Type | Small organic molecule |
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| Emp. Form. | C13H21N3 |
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| Mol. Mass. | 219.3259 |
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| SMILES | CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 |r| |
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| Structure | 
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