| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-arrestin-2 |
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| Ligand | BDBM50136166 |
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| Substrate/Competitor | n/a |
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| Ki | 3630.78±n/a nM |
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| Comments | PDSP_832 |
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| Citation |  Wong, DT; Threlkeld, PG; Robertson, DW Affinities of fluoxetine, its enantiomers, and other inhibitors of serotonin uptake for subtypes of serotonin receptors. Neuropsychopharmacology5:43-7 (1991) [PubMed] |
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| More Info.: | Get all data from this article |
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| Beta-arrestin-2 |
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| Name: | Beta-arrestin-2 |
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| Synonyms: | 5-HT2C | ARRB2 | ARRB2_BOVIN | Beta-arrestin-2 | HTR2C |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47232.00 |
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| Organism: | Beef |
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| Description: | 5-HT2C HTR2C Beef::P32120 |
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| Residue: | 420 |
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| Sequence: | MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTC
AFRYGREDLDVLGLSFRKDLFIANYQAFPPTPNPPRPPTRLQERLLRKLGQHAHPFFFTI
PQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPG
PQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYA
DICLFSTAQYKCPVAQVEQDDQVSPSSTFCKVYTITPLLSNNREKRGLALDGKLKHEDTN
LASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIALPRPQS
AATHPPTLLPSAVPETDAPVDTNLIEFETNYATDDDIVFEDFARLRLKGLKDEDYDDQFC
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| BDBM50136166 |
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| n/a |
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| Name | BDBM50136166 |
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| Synonyms: | (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine | (R)-fluoxetine | CHEMBL153036 | FLUOXETINE | Methyl-[(R)-3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amine | Methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18F3NO |
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| Mol. Mass. | 309.3261 |
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| SMILES | CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1 |r| |
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| Structure | 
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