| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-arrestin-2 |
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| Ligand | BDBM22416 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_1439 |
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| Citation |  Wong, DT; Threlkeld, PG; Robertson, DW Affinities of fluoxetine, its enantiomers, and other inhibitors of serotonin uptake for subtypes of serotonin receptors. Neuropsychopharmacology5:43-7 (1991) [PubMed] |
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| More Info.: | Get all data from this article |
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| Beta-arrestin-2 |
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| Name: | Beta-arrestin-2 |
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| Synonyms: | 5-HT2C | ARRB2 | ARRB2_BOVIN | Beta-arrestin-2 | HTR2C |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47232.00 |
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| Organism: | Beef |
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| Description: | 5-HT2C HTR2C Beef::P32120 |
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| Residue: | 420 |
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| Sequence: | MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTC
AFRYGREDLDVLGLSFRKDLFIANYQAFPPTPNPPRPPTRLQERLLRKLGQHAHPFFFTI
PQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPG
PQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYA
DICLFSTAQYKCPVAQVEQDDQVSPSSTFCKVYTITPLLSNNREKRGLALDGKLKHEDTN
LASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIALPRPQS
AATHPPTLLPSAVPETDAPVDTNLIEFETNYATDDDIVFEDFARLRLKGLKDEDYDDQFC
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| BDBM22416 |
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| n/a |
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| Name | BDBM22416 |
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| Synonyms: | (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine | (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine | CHEMBL490 | PAROXETINE | US09969700, Paroxetine | US9944618, Compound ID No. 182 | [3H]Paroxetine |
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| Type | radiolabeled ligand |
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| Emp. Form. | C19H20FNO3 |
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| Mol. Mass. | 329.3654 |
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| SMILES | Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1 |
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| Structure | 
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