| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase A1 |
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| Ligand | BDBM81907 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Ki | 4.20e+5±n/a nM |
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| Citation |  Fernández, D; Avilés, FX; Vendrell, J Aromatic organic compounds as scaffolds for metallocarboxypeptidase inhibitor design. Chem Biol Drug Des73:75-82 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase A1 |
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| Name: | Carboxypeptidase A1 |
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| Synonyms: | CBPA1_BOVIN | CPA | CPA1 | Carboxypeptidase A | Carboxypeptidase A (CPA) | Carboxypeptidase A1 precursor |
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| Type: | Enzyme |
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| Mol. Mass.: | 47073.90 |
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| Organism: | Bos taurus (bovine) |
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| Description: | From Sigma-Aldrich Co. |
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| Residue: | 419 |
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| Sequence: | MQGLLILSVLLGAALGKEDFVGHQVLRITAADEAEVQTVKELEDLEHLQLDFWRGPGQPG
SPIDVRVPFPSLQAVKVFLEAHGIRYRIMIEDVQSLLDEEQEQMFASQSRARSTNTFNYA
TYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNRPAIWIDLGIHS
REWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLWRKTR
SVTSSSLCVGVDANRNWDAGFGKAGASSSPCSETYHGKYANSEVEVKSIVDFVKDHGNFK
AFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVEALKSLYGTSYKYGSIITTIYQA
SGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTIMEHTLNNLY
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| BDBM81907 |
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| n/a |
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| Name | BDBM81907 |
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| Synonyms: | 1-(2-hydroxyethyl)-1-((6-methoxy-2-oxo-1,2-dihydroquinolin-3-yl)methyl)3-yl)methyl)-3-p-tolythiourea, 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H23N3O3S |
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| Mol. Mass. | 397.491 |
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| SMILES | COc1ccc2[nH]c(=O)c(CN(CCO)C(=S)Nc3ccc(C)cc3)cc2c1 |
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| Structure | 
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