| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carboxypeptidase B |
|---|
| Ligand | BDBM81905 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| Ki | 4.1e+3±n/a nM |
|---|
| Citation |  Fernández, D; Avilés, FX; Vendrell, J Aromatic organic compounds as scaffolds for metallocarboxypeptidase inhibitor design. Chem Biol Drug Des73:75-82 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carboxypeptidase B |
|---|
| Name: | Carboxypeptidase B |
|---|
| Synonyms: | CPB |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48382.46 |
|---|
| Organism: | Helicoverpa zea (Corn earworm moth) (Heliothis zea) |
|---|
| Description: | Q3T905 |
|---|
| Residue: | 429 |
|---|
| Sequence: | MKFLLVLALCAVVYAKHEAYIGWKSYYVGVATDAQAKALEPLIQKYELDFLSHPTKSREG
VVLVKPQHQAGFVQDIEAGGITYRIHADDVKRQLEFDDQLIEMQRMSSFTRTAGRQLPYD
NYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFIDGG
IHAREWISPPSVTWAIHKLVEDVTENDLLEKFDWILLPVVNPDGYKYTFTNERFWRKTRS
TNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRDILHEHLA
RMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPYTVGNSA
LVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWEGIVVGA
RRAGDLFRK
|
|
|
|---|
| BDBM81905 |
|---|
| n/a |
|---|
| Name | BDBM81905 |
|---|
| Synonyms: | 1-(3,4-dihydroisoquinolin-1(1H)-yl)-2-(5-(3,5-dimethylphenyl)-1,3,4-oxadiazol-2-ylthio)ethanone, 4 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H21N3O2S |
|---|
| Mol. Mass. | 379.475 |
|---|
| SMILES | Cc1cc(C)cc(c1)-c1nnc(SCC(=O)N2CCCc3ccccc23)o1 |
|---|
| Structure | 
|
|---|
Search and Browse
