| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50006730 |
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| Substrate/Competitor | n/a |
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| Ki | 8.3±n/a nM |
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| Comments | PDSP_1738 |
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| Citation |  Klotz, KN; Vogt, H; Tawfik-Schlieper, H Comparison of A1 adenosine receptors in brain from different species by radioligand binding and photoaffinity labelling. Naunyn Schmiedebergs Arch Pharmacol343:196-201 (1991) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | AA3R_SHEEP | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADENOSINE A3 | ADORA1 | ADORA3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36152.74 |
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| Organism: | Sheep |
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| Description: | ADENOSINE A1 ADORA1 Sheep::P35342 |
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| Residue: | 317 |
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| Sequence: | MPVNSTAVSWTSVTYITVEILIGLCAIVGNVLVIWVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVISLGVTIHFYSCLFMTCLMLIFTHASIMSLLAIAVDRYLRVKLTVRYRR
VTTQRRIWLALGLCWLVSFLVGLTPMFGWNMKLSSADENLTFLPCRFRSVMRMDYMVYFS
FFLWILVPLVVMCAIYFDIFYIIRNRLSQSFSGSRETGAFYGREFKTAKSLLLVLFLFAL
CWLPLSIINCILYFDGQVPQTVLYLGILLSHANSMMNPIVYAYKIKKFKETYLLILKACV
MCQPSKSMDPSTEQTSE
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| BDBM50006730 |
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| n/a |
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| Name | BDBM50006730 |
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| Synonyms: | (R)-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | (R-PIa) 2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | (S)-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | 2-(hydroxymethyl)-5-{6-[(1-phenylpropan-2-yl)amino]-9H-purin-9-yl}oxolane-3,4-diol | 2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | CHEMBL274022 | ChEMBL_20163 | D-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | L-2-Hydroxymethyl-5-[6-(1-methyl-2-phenyl-ethylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol | R-N6-(2-phenylisopropyl) adenosine | R-PIA | S-PIA |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23N5O4 |
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| Mol. Mass. | 385.417 |
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| SMILES | CC(Cc1ccccc1)Nc1ncnc2n(cnc12)C1OC(CO)C(O)C1O |
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| Structure | 
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