| Reaction Details |
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 | Report a problem with these data |
| Target | Substance-K receptor |
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| Ligand | BDBM50194558 |
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| Substrate/Competitor | n/a |
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| Ki | 15±n/a nM |
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| Comments | PDSP_778 |
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| Citation |  Burcher, E; Buck, SH; Lovenberg, W; O'Donohue, TL Characterization and autoradiographic localization of multiple tachykinin binding sites in gastrointestinal tract and bladder. J Pharmacol Exp Ther236:819-31 (1986) [PubMed] |
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| More Info.: | Get all data from this article |
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| Substance-K receptor |
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| Name: | Substance-K receptor |
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| Synonyms: | NK2R_CAVPO | Neurokinin 2 receptor | Neurokinin NK2 | Substance-K receptor | TACR2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45106.00 |
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| Organism: | GUINEA PIG |
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| Description: | Neurokinin NK2 TACR2 GUINEA PIG::Q64077 |
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| Residue: | 402 |
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| Sequence: | MGACVIVTNTNISSGLESNTTGITAFSMPTWQLALWATAYLALVLVAVTGNATVTWIILA
HQRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
IYSMTAIAIDRYMAIVHPFQPRLSAPSTKAVIGGIWLVALALAFPQCFYSTITEDEGATK
CVVAWPEDSRDKSLLLYHLVVIVLIYLLPLTVMFVAYSIIGLTLWRRAVPRHQAHGANLR
HLQAKKKFVKTMVLVVVTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST
MYNPIIYCCLNRRFRSGFRLAFRCCPWVTPTEEDKLELTHTPSFSLRVNRCHTKEILFMA
GDTVPSEATNGQAGGPQDRESVELSSLPGCRAGPSILAKASS
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| BDBM50194558 |
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| n/a |
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| Name | BDBM50194558 |
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| Synonyms: | CHEMBL373569 | ELEDOISIN |
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| Type | Small organic molecule |
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| Emp. Form. | C54H85N13O15S |
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| Mol. Mass. | 1188.396 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCC(=O)N1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
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| Structure | 
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