Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetNorepinephrine transporter
LigandBDBM22165
Substrate/Competitorn/a
Ki 440±n/a nM
CommentsPDSP_870
Citation Andersen, PH The dopamine inhibitor GBR 12909: selectivity and molecular mechanism of action. Eur J Pharmacol166:493-504 (1989) [PubMed]  Article
More Info.:Get all data from this article
 
Norepinephrine transporter
Name:Norepinephrine transporter
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:2082.45
Organism:RAT
Description:Norepinephrine transporter 0 RAT::Q9JIA2
Residue:19
Sequence:
MLLARMKPQVQPELGGADQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM22165
n/a
NameBDBM22165
Synonyms:1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine | CHEMBL153260 | CHEMBL281594 | CHEMBL542933 | CHEMBL543876 | GBR 12909 | GBR-12909 | NCGC00015300 | US9944618, Compound ID No. 175 | Vanoxerine
TypeSmall organic molecule
Emp. Form.C28H32F2N2O
Mol. Mass.450.5633
SMILESFc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: