| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
|---|
| Ligand | BDBM50019848 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 3±n/a nM |
|---|
| Comments | PDSP_959 |
|---|
| Citation |  Hieble, JP; DeMarinis, RM; Fowler, PJ; Matthews, WD Selective alpha-2 adrenoceptor blockade by SK&F 86466: in vitro characterization of receptor selectivity. J Pharmacol Exp Ther236:90-6 (1986) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Alpha-2A adrenergic receptor |
|---|
| Name: | Alpha-2A adrenergic receptor |
|---|
| Synonyms: | ADA2A_CAVPO | ADRA2A | Alpha-2A adrenergic receptor | adrenergic Alpha2 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 48933.12 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | adrenergic Alpha2 0 GUINEA PIG::Q60474 |
|---|
| Residue: | 450 |
|---|
| Sequence: | MGSLQPDSGNASWNGTEGPGGGTRATPYSLQVTVTLVCLVGLLILLTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKAGGGGQ
QPAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAHAA
APPGGAERRPNGLGLERGVGPGGAEAEPLPTQVNGAPGEPAPAGPRDAEALDLEESSSSE
HAERPPGARRPERGLRAKSKARASQVKPGDSLPRRAPGAAGSGTSGSGPGEERGGGAKAS
RWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSS
LNPVIYTIFNHDFRRAFKKILCRGDRKRIV
|
|
|
|---|
| BDBM50019848 |
|---|
| n/a |
|---|
| Name | BDBM50019848 |
|---|
| Synonyms: | 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole | 4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole | CHEMBL10316 | Idazoxan | US8633208, Idazoxan |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H12N2O2 |
|---|
| Mol. Mass. | 204.2252 |
|---|
| SMILES | C1CN=C(N1)C1COc2ccccc2O1 |c:2| |
|---|
| Structure | 
|
|---|
Search and Browse
