| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
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| Ligand | BDBM35256 |
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| Substrate/Competitor | n/a |
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| Ki | 2.8±n/a nM |
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| Comments | PDSP_1235 |
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| Citation |  Nicklaus, KJ; McGonigle, P; Molinoff, PB [3H]SCH 23390 labels both dopamine-1 and 5-hydroxytryptamine1c receptors in the choroid plexus. J Pharmacol Exp Ther247:343-8 (1988) [PubMed] |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 2C |
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| Name: | 5-hydroxytryptamine receptor 2C |
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| Synonyms: | 5-HT2C | 5-hydroxytryptamine receptor 2C | 5HT2C_CANLF | HTR2C |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51858.52 |
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| Organism: | CANINE |
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| Description: | 5-HT2C HTR2C CANINE::Q60F97 |
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| Residue: | 458 |
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| Sequence: | MVNLRKAVHSFLVHLIGLLVWQCDISVSPVAALVTDIFNTSDGGRFKFPDGVQNWPALSI
VIIIILTIGGNILVIMAVSLEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW
PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPVEHSRFNSRTKAIMKIAIVWA
ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIHV
LRRQALMLLHGHVEEPPRINLDFLKCCRRNGTEEENSANPNQDSNPRRRKKKERRPRGTM
QAINNERKASKVLGIVFFVFLVMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVC
SGINPLVYTLFNKIYRRAFSNYLRCNYKPEKKPPVRQMPRVAATALSGRELNVNIYRHTN
EPVLKKANDKEPGIEMQVENLELPVNPSSVVSERISSV
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| BDBM35256 |
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| n/a |
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| Name | BDBM35256 |
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| Synonyms: | (S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+) | MIANSERIN (-) | Tolvon |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N2 |
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| Mol. Mass. | 264.3648 |
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| SMILES | [H][C@]12CN(C)CCN1c1ccccc1Cc1ccccc21 |r| |
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| Structure | 
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