| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A1 |
|---|
| Ligand | BDBM82012 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 3.4±n/a nM |
|---|
| Comments | PDSP_2817 |
|---|
| Citation |  Schwabe, U; Ukena, D; Lohse, MJ Xanthine derivatives as antagonists at A1 and A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol330:212-21 (1985) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Adenosine receptor A1 |
|---|
| Name: | Adenosine receptor A1 |
|---|
| Synonyms: | AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 36602.99 |
|---|
| Organism: | BOVINE |
|---|
| Description: | ADENOSINE 0 BOVINE::P28190 |
|---|
| Residue: | 326 |
|---|
| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPVDEDAPAERPDD
|
|
|
|---|
| BDBM82012 |
|---|
| n/a |
|---|
| Name | BDBM82012 |
|---|
| Synonyms: | 8-(4-Hydroxy-phenyl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione | 8-(4-hydroxyphenyl)theophylline | CHEMBL27047 |
|---|
| Type | n/a |
|---|
| Emp. Form. | C13H12N4O3 |
|---|
| Mol. Mass. | 272.2594 |
|---|
| SMILES | Cn1c2nc([nH]c2c(=O)n(C)c1=O)-c1ccc(O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
