| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1A adrenergic receptor |
|---|
| Ligand | BDBM35256 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 54.95±n/a nM |
|---|
| Comments | PDSP_3347 |
|---|
| Citation |  de Boer, TH; Maura, G; Raiteri, M; de Vos, CJ; Wieringa, J; Pinder, RM Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, Org 3770 and its enantiomers. Neuropharmacology27:399-408 (1988) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Alpha-1A adrenergic receptor |
|---|
| Name: | Alpha-1A adrenergic receptor |
|---|
| Synonyms: | ADA1A_RAT | Adra1a | Adra1c | Alpha-1 adrenoreceptor | Alpha-1A adrenoceptor | Alpha-1A adrenoreceptor | Alpha-1C adrenergic receptor | adrenergic Alpha1A |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 51620.15 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P43140 |
|---|
| Residue: | 466 |
|---|
| Sequence: | MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
VPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTL
HPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACT
TARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
|
|
|
|---|
| BDBM35256 |
|---|
| n/a |
|---|
| Name | BDBM35256 |
|---|
| Synonyms: | (S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+) | MIANSERIN (-) | Tolvon |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H20N2 |
|---|
| Mol. Mass. | 264.3648 |
|---|
| SMILES | [H][C@]12CN(C)CCN1c1ccccc1Cc1ccccc21 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
