Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histamine H1 receptor | ||
| Ligand | BDBM50005548 | ||
| Substrate/Competitor | n/a | ||
| Ki | >10000±n/a nM | ||
| Comments | PDSP_1347 | ||
| Citation |  Wong, DT; Threlkeld, PG; Best, KL; Bymaster, FP A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain. J Pharmacol Exp Ther222:61-5 (1982) [PubMed] | ||
| More Info.: | Get all data from this article | ||
| Histamine H1 receptor | |||
| Name: | Histamine H1 receptor | ||
| Synonyms: | HISTAMINE H1 | HRH1_RAT | Hrh1 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 55716.35 | ||
| Organism: | RAT | ||
| Description: | HISTAMINE H1 HRH1 RAT::P31390 | ||
| Residue: | 486 | ||
| Sequence: |
| ||
| BDBM50005548 | |||
| n/a | |||
| Name | BDBM50005548 | ||
| Synonyms: | (+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | (+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | (-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | (Nomifensine) 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine (Nomifensine) | 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine(Nomifensine) | 2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine | CHEMBL273575 | NOMIFENSINE | NOMIFENSINE2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H18N2 | ||
| Mol. Mass. | 238.3275 | ||
| SMILES | CN1CC(c2ccccc2)c2cccc(N)c2C1 | ||
| Structure | 
| ||