| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase Blk |
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| Ligand | BDBM3044 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TPK assay |
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| IC50 | >10000±n/a nM |
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| Citation |  Kleinschroth, J; Hartenstein, J; Rudolph, C; Schachtele, C Novel Indolocarbazole protein kinase C inhibitors with improved biochemical and physicochemical properties. Bioorg Med Chem Lett5:55-60 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase Blk |
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| Name: | Tyrosine-protein kinase Blk |
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| Synonyms: | B lymphocyte kinase | BLK_MOUSE | Blk | p55-Blk |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56676.10 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_810654 |
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| Residue: | 499 |
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| Sequence: | MGLLSSKRQVSEKGKGWSPVKIRTQDKAPPPLPPLVVFNHLAPPSPNQDPDEEERFVVAL
FDYAAVNDRDLQVLKGEKLQVLRSTGDWWLARSLVTGREGYVPSNFVAPVETLEVEKWFF
RTISRKDAERQLLAPMNKAGSFLIRESESNKGAFSLSVKDITTQGEVVKHYKIRSLDNGG
YYISPRITFPTLQALVQHYSKKGDGLCQKLTLPCVNLAPKNLWAQDEWEIPRQSLKLVRK
LGSGQFGEVWMGYYKNNMKVAIKTLKEGTMSPEAFLGEANVMKTLQHERLVRLYAVVTRE
PIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQVAEGMAYIERMNSIHRDLRAANI
LVSETLCCKIADFGLARIIDSEYTAQEGAKFPIKWTAPEAIHFGVFTIKADVWSFGVLLM
EIVTYGRVPYPGMSNPEVIRSLEHGYRMPCPETCPPELYNDIITECWRGRPEERPTFEFL
QSVLEDFYTATEGQYELQP
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| BDBM3044 |
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| n/a |
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| Name | BDBM3044 |
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| Synonyms: | 3-{7-methoxy-23-methyl-12,14-dioxo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17,19,21-nonaen-3-yl}propanenitrile | Indolocarbazole deriv. 3l |
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| Type | Small organic molecule |
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| Emp. Form. | C25H18N4O3 |
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| Mol. Mass. | 422.4354 |
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| SMILES | COc1ccc2n(CCC#N)c3c(c4C(=O)NC(=O)c4c4c5ccccc5n(C)c34)c2c1 |
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| Structure | 
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