| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM81468 |
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| Substrate/Competitor | n/a |
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| Ki | 510±n/a nM |
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| Comments | PDSP_1231 |
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| Citation |  Gajtkowski, GA; Norris, DB; Rising, TJ; Wood, TP Specific binding of 3H-tiotidine to histamine H2 receptors in guinea pig cerebral cortex. Nature304:65-7 (1983) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_CAVPO | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40567.22 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | For the H2 receptor-binding assays, guinea pig striatum was used. |
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| Residue: | 359 |
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| Sequence: | MAFNGTVPSFCMDFTVYKVTISVILIILILVTVAGNVVVCLAVGLNRRLRSLTNCFIVSL
AVTDLLLGLLVLPFSAIYQLSCKWSFSKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLITPARVAISLVFIWVISITLSFLSIHLGWNSRNETSKDNDTIVKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYFRIFKIAREQARRINHIGSWKAATIREHKATVTLAAVM
GAFIICWFPYFTVFVYRGLKGDDAVNEVFEDVVLWLGYANSALNPILYAALNRDFRTAYH
QLFCCRLASHNSHETSLRLNNSQLNRSQCQEPRWQEDKPLNLQVWSGTEVTAPQGATNR
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| BDBM81468 |
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| n/a |
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| Name | BDBM81468 |
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| Synonyms: | CAS_34839-70-8 | Metiamide | NSC_1548992 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H16N4S2 |
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| Mol. Mass. | 244.38 |
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| SMILES | CNC(=S)NCCSCc1[nH]cnc1C |
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| Structure | 
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