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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histamine H1 receptor | ||
| Ligand | BDBM50000693 | ||
| Substrate/Competitor | n/a | ||
| Ki | >10000±n/a nM | ||
| Comments | PDSP_365 | ||
| Citation |  Kanba, S; Richelson, E Histamine H1 receptors in human brain labelled with [3H]doxepin. Brain Res304:1-7 (1984) [PubMed] Article | ||
| More Info.: | Get all data from this article | ||
| Histamine H1 receptor | |||
| Name: | Histamine H1 receptor | ||
| Synonyms: | H1R | HH1R | HISTAMINE H1 | HRH1 | HRH1_HUMAN | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 55808.72 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Cell pellets from SK-N-MC cells transfected with human H1 receptor were used in binding assay. | ||
| Residue: | 487 | ||
| Sequence: |
| ||
| BDBM50000693 | |||
| n/a | |||
| Name | BDBM50000693 | ||
| Synonyms: | (R)-6-((S)-6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one | (R)-6-((S)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuro[5,4-d][1,3]dioxol-8(6H)-one | (bicuculline) 6-Methyl-5-(8-oxo-6,8-dihydro-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-6-yl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium | 6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one | 6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one (Bicuculline) | 6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one(bicuculline) | Bicuculline,(+) | CHEMBL417990 | bicuculline | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H17NO6 | ||
| Mol. Mass. | 367.3521 | ||
| SMILES | CN1CCc2cc3OCOc3cc2[C@H]1[C@@H]1OC(=O)c2c1ccc1OCOc21 |r| | ||
| Structure | 
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