| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H1 receptor |
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| Ligand | BDBM50240424 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_801 |
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| Citation |  Kanba, S; Richelson, E Histamine H1 receptors in human brain labelled with [3H]doxepin. Brain Res304:1-7 (1984) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Histamine H1 receptor |
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| Name: | Histamine H1 receptor |
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| Synonyms: | H1R | HH1R | HISTAMINE H1 | HRH1 | HRH1_HUMAN |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 55808.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Cell pellets from SK-N-MC cells transfected with human H1 receptor were used in binding assay. |
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| Residue: | 487 |
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| Sequence: | MSLPNSSCLLEDKMCEGNKTTMASPQLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHT
VGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFI
LCIDRYRSVQQPLRYLKYRTKTRASATILGAWFLSFLWVIPILGWNHFMQQTSVRREDKC
ETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINRSLPSFSEIKLR
PENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKL
YCFPLDIVHMQAAAEGSSRDYVAVNRSHGQLKTDEQGLNTHGASEISEDQMLGDSQSFSR
TDSDTTTETAPGKGKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFI
MAAFILCWIPYFIFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFK
RILHIRS
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| BDBM50240424 |
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| n/a |
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| Name | BDBM50240424 |
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| Synonyms: | 3-Ethyl-3-methyl-pyrrolidine-2,5-dione | 3-Ethyl-3-methyl-pyrrolidine-2,5-dione (ethosuximide) | 3-Ethyl-3-methyl-pyrrolidine-2,5-dione(ethosuximide) | 3-ethyl-3-methylpyrrolidine-2,5-dione | CHEMBL696 | CI-366 | CN-10395 | ETHOSUXIMIDE | PM-671 | Zarontin | zarontin3-Ethyl-3-methyl-pyrrolidine-2,5-dione |
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| Type | Small organic molecule |
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| Emp. Form. | C7H11NO2 |
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| Mol. Mass. | 141.1677 |
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| SMILES | CCC1(C)CC(=O)NC1=O |
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| Structure | 
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