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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histamine H1 receptor | ||
| Ligand | BDBM28347 | ||
| Substrate/Competitor | n/a | ||
| Ki | 5.8±n/a nM | ||
| Comments | PDSP_1203 | ||
| Citation |  Kanba, S; Richelson, E Histamine H1 receptors in human brain labelled with [3H]doxepin. Brain Res304:1-7 (1984) [PubMed] Article | ||
| More Info.: | Get all data from this article | ||
| Histamine H1 receptor | |||
| Name: | Histamine H1 receptor | ||
| Synonyms: | H1R | HH1R | HISTAMINE H1 | HRH1 | HRH1_HUMAN | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 55808.72 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Cell pellets from SK-N-MC cells transfected with human H1 receptor were used in binding assay. | ||
| Residue: | 487 | ||
| Sequence: |
| ||
| BDBM28347 | |||
| n/a | |||
| Name | BDBM28347 | ||
| Synonyms: | 3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2.2]octan-1-ium | Mequitazine | ZINC01567421, 6 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H23N2S | ||
| Mol. Mass. | 323.474 | ||
| SMILES | C(C1C[NH+]2CCC1CC2)N1c2ccccc2Sc2ccccc12 |THB:0:1:5.4:7.8,(14.51,-5.48,;15.79,-4.74,;17.21,-5.13,;17.6,-2.22,;20.16,-.74,;19.42,.54,;16.17,-1.84,;14.72,-.36,;16,.37,;14.51,-6.96,;15.79,-7.7,;17.11,-6.91,;18.45,-7.67,;18.45,-9.21,;17.11,-9.97,;15.79,-9.18,;14.51,-9.92,;13.22,-9.18,;11.9,-9.97,;10.56,-9.21,;10.56,-7.67,;11.9,-6.91,;13.22,-7.7,)| | ||
| Structure | 
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