Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetProstanoid IP receptor
LigandBDBM82097
Substrate/Competitorn/a
Ki 7350±n/a nM
CommentsPDSP_5307
Citation Blair IAMacDermot J The binding of [3H]-prostacyclin to membranes of a neuronal somatic hybrid. Br J Pharmacol 72:435-41 (1981) [PubMed]  Article
More Info.:Get all data from this article
 
Prostanoid IP receptor
Name:Prostanoid IP receptor
Synonyms:PGI receptor | Prostacyclin (IP) Receptor | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Prostaglandin I2 receptor
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40968.22
Organism:Homo sapiens (Human)
Description:The membranes prepared from human platelet were used in binding assay.
Residue:386
Sequence:
MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD
LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA
LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG
GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL
LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF
QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL
PPTQQSSGSAVGTSSKAEASVACSLC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM82097
n/a
NameBDBM82097
Synonyms:CAS_162981 | NSC_162981 | PGI1, 6beta
TypeSmall organic molecule
Emp. Form.C20H34O5
Mol. Mass.354.481
SMILESCCCCCC(O)C=CC1C(O)CC2OC(CCCCC(O)=O)CC12 |w:7.6|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: