| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM21395 |
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| Substrate/Competitor | n/a |
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| Ki | 880±n/a nM |
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| Comments | PDSP_1583 |
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| Citation |  Zahniser, NR; Dubocovich, ML Comparison of dopamine receptor sites labeled by [3H]-S-sulpiride and [3H]-spiperone in striatum. J Pharmacol Exp Ther227:592-9 (1983) [PubMed] |
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| More Info.: | Get all data from this article |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DRD2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50660.69 |
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| Organism: | RABBIT |
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| Description: | DOPAMINE D2 DRD2 RABBIT::G1T1Q0 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDEDLERQNWSRPLNGSEGRGDRPHYNYYAMLLTLLIFVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRVHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSLTISCPLLFGLNKTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLRAPL
KGNCTHPEDRTLGTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFMKILHC
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| BDBM21395 |
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| n/a |
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| Name | BDBM21395 |
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| Synonyms: | 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione | 3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione | CHEMBL1628637 | CHEMBL51 | Ketanserin | R-41,468 | R-41-468 | R41,468 | [3H]-Ketanserin |
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| Type | radiolabeled ligand |
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| Emp. Form. | C22H22FN3O3 |
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| Mol. Mass. | 395.4268 |
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| SMILES | Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 |
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| Structure | 
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