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Reaction Details
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Target5-hydroxytryptamine 1D receptor
LigandBDBM50252513
Substrate/Competitorn/a
Ki 117±n/a nM
CommentsPDSP_1600
Citation Leysen, JEJanssen, PMMegens, AASchotte, A Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity. J Clin Psychiatry0:5-12 (1994) [PubMed]
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5-hydroxytryptamine 1D receptor
Name:5-hydroxytryptamine 1D receptor
Synonyms:5-hydroxytryptamine 1D receptor (5HT1D) | HTR1D
Type:Protein
Mol. Mass.:12731.52
Organism:Bos taurus (Bovine)
Description:Q8MI13
Residue:119
Sequence:
SNRSLNATATQGAWDPGTLQALKIALVVLLSIITLATVLSNAFVLTTIFLTRKLHTPANC
LIGSLAMTDLLVSILVMPISIAYTTTHTWSFGQLLCDIWLSSDITCCTASILHLCVIAL
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BDBM50252513
n/a
NameBDBM50252513
Synonyms:3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one | 9-OH-risperidone | 9-hydroxy risperidone | CHEMBL1621 | Invega | PALIPERIDONE
TypeSmall organic molecule
Emp. Form.C23H27FN4O3
Mol. Mass.426.4839
SMILESCc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12
Structure
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