| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM82351 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Sigma 1 Assay |
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| pH | 7.4±0 |
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| Temperature | 310.15±0 K |
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| Ki | 14.2±4 nM |
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| Citation |  Yarim, M; Koksal, M; Schepmann, D; Wünsch, B Synthesis and in vitro Evaluation of Novel Indole-Based Sigma Receptors Ligands. Chem Biol Drug Des78:869-75 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM82351 |
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| n/a |
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| Name | BDBM82351 |
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| Synonyms: | 1-{[4-(substitutedphenyl/phenylethyl)piperazin1-yl]methyl}-3-methyl-1 H-indole, 3b |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27N3 |
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| Mol. Mass. | 333.4699 |
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| SMILES | Cc1cn(CN2CCN(CCc3ccccc3)CC2)c2ccccc12 |
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| Structure | 
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