| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M4 |
|---|
| Ligand | BDBM50151858 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 2.69±n/a nM |
|---|
| Comments | PDSP_3904 |
|---|
| Citation |  Lazareno, S; Buckley, NJ; Roberts, FF Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. Mol Pharmacol38:805-15 (1990) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Muscarinic acetylcholine receptor M4 |
|---|
| Name: | Muscarinic acetylcholine receptor M4 |
|---|
| Synonyms: | ACM4_CHICK | CHRM4 | Cholinergic, muscarinic M4 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 54968.10 |
|---|
| Organism: | Chick |
|---|
| Description: | Cholinergic, muscarinic M4 CHRM4 Chick::P17200 |
|---|
| Residue: | 490 |
|---|
| Sequence: | MHNLSAQPWQAKMANLTYDNVTLSNRSEVAIQPPTNYKTVELVFIATVTGSLSLVTVVGN
ILVMLSIKVNRQLQTVNNYFLFSLACADLIIGVFSMNLYTVYIIKGYWPLGAVVCDLWLA
LDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWILSFILWAPAILF
WQFIVGKRTVHERECYIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVRRHK
PESRKERKGKSLSFFKAPPVKQNNNNSPKRAVEVKEEVRNGKVDDQPSAQTEATGQQEEK
ETSNESSTVSMTQTTKDKPTTEILPAGQGQSPAHPRVNPTSKWSKIKIVTKQTGTESVTA
IEIVPAKAGASDHNSLSNSRPANVARKFASIARSQVRKKRQMAAREKKVTRTIFAILLAF
ILTWTPYNVMVLINTFCETCVPETVWSIGYWLCYVNSTINPACYALCNATFKKTFKHLLM
CQYRNIGTAR
|
|
|
|---|
| BDBM50151858 |
|---|
| n/a |
|---|
| Name | BDBM50151858 |
|---|
| Synonyms: | 4-(diethylamino)but-2-yn-1-yl (2S)-cyclohexyl(hydroxy)phenylacetate | CHEMBL185434 | OXYBUTYNIN | esoxybutynin |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H31NO3 |
|---|
| Mol. Mass. | 357.4864 |
|---|
| SMILES | CCN(CC)CC#CCOC(=O)[C@@](O)(C1CCCCC1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
