| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2C adrenergic receptor |
|---|
| Ligand | BDBM81814 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 1±n/a nM |
|---|
| Comments | PDSP_1711 |
|---|
| Citation |  Megens, AA; Leysen, JE; Awouters, FH; Niemegeers, CJ Further validation of in vivo and in vitro pharmacological procedures for assessing the alpha 2/alpha 1-selectivity of test compounds: (1). Alpha-adrenoceptor antagonists. Eur J Pharmacol129:49-55 (1986) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Alpha-2C adrenergic receptor |
|---|
| Name: | Alpha-2C adrenergic receptor |
|---|
| Synonyms: | ADA2C_RAT | Adra2c | Adrenergic receptor alpha | Alpha-2C adrenergic receptor | adrenergic Alpha2 | adrenergic Alpha2C |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49890.50 |
|---|
| Organism: | RAT |
|---|
| Description: | adrenergic Alpha2 0 RAT::P22086 |
|---|
| Residue: | 458 |
|---|
| Sequence: | MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPPPGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRR
GGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRAR
SSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFW
IGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
|
|
|
|---|
| BDBM81814 |
|---|
| n/a |
|---|
| Name | BDBM81814 |
|---|
| Synonyms: | 5H-THIAZOLO[3,2A]PYRIMIDIN-5-ONE, 6-[2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL]-2,3-DIHYDRO-7-METHYL- | CAS_86487-64-1 | SEPTOPERONE | SETOPERONE |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H24FN3O2S |
|---|
| Mol. Mass. | 401.498 |
|---|
| SMILES | Cc1nc2SCCn2c(=O)c1CCN1CCC(CC1)C(=O)c1ccc(F)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
