| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin |
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| Ligand | BDBM50019808 |
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| Substrate/Competitor | n/a |
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| Ki | 300±n/a nM |
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| Comments | PDSP_9 |
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| Citation |  Evans, BE; Bock, MG; Rittle, KE; DiPardo, RM; Whitter, WL; Veber, DF; Anderson, PS; Freidinger, RM Design of potent, orally effective, nonpeptidal antagonists of the peptide hormone cholecystokinin. Proc Natl Acad Sci U S A83:4918-22 (1986) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| |
| Cholecystokinin |
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| Name: | Cholecystokinin |
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| Synonyms: | CCKN_RAT | Cck |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12844.29 |
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| Organism: | RAT |
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| Description: | Cholecystokinin 0 RAT::P01355 |
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| Residue: | 115 |
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| Sequence: | MKCGVCLCVVMAVLAAGALAQPVVPVEAVDPMEQRAEEAPRRQLRAVLRPDSEPRARLGA
LLARYIQQVRKAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDFGRRSAEDYEYPS
|
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|
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| BDBM50019808 |
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| n/a |
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| Name | BDBM50019808 |
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| Synonyms: | (R)6-(2-Fluoro-phenyl)-4-(1H-indol-3-ylmethyl)-1-methyl-4H-2,3,5,10b-tetraaza-benzo[e]azulene | CCK antagonist synthetic 12 | CHEMBL278777 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H20FN5 |
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| Mol. Mass. | 421.4689 |
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| SMILES | Cc1nnc2C(Cc3c[nH]c4ccccc34)N=C(c3ccccc3F)c3ccccc3-n12 |t:18| |
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| Structure | 
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