| Reaction Details |
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 | Report a problem with these data |
| Target | Cholecystokinin |
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| Ligand | BDBM50019260 |
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| Substrate/Competitor | n/a |
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| Ki | 2.1±n/a nM |
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| Comments | PDSP_45 |
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| Citation |  Evans, BE; Bock, MG; Rittle, KE; DiPardo, RM; Whitter, WL; Veber, DF; Anderson, PS; Freidinger, RM Design of potent, orally effective, nonpeptidal antagonists of the peptide hormone cholecystokinin. Proc Natl Acad Sci U S A83:4918-22 (1986) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| |
| Cholecystokinin |
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| Name: | Cholecystokinin |
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| Synonyms: | CCKN_RAT | Cck |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12844.29 |
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| Organism: | RAT |
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| Description: | Cholecystokinin 0 RAT::P01355 |
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| Residue: | 115 |
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| Sequence: | MKCGVCLCVVMAVLAAGALAQPVVPVEAVDPMEQRAEEAPRRQLRAVLRPDSEPRARLGA
LLARYIQQVRKAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDFGRRSAEDYEYPS
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| BDBM50019260 |
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| n/a |
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| Name | BDBM50019260 |
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| Synonyms: | 1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-amide | 1H-Indole-2-carboxylic acid [5-(2-fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-amide: 0.16CH2Cl2 | CCK antagonist synthetic 21 | CHEMBL306806 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H17FN4O2 |
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| Mol. Mass. | 412.4158 |
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| SMILES | Fc1ccccc1C1=NC(NC(=O)c2cc3ccccc3[nH]2)C(=O)Nc2ccccc12 |t:8| |
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| Structure | 
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