| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 1 |
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| Ligand | BDBM50033111 |
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| Substrate/Competitor | n/a |
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| Ki | 31.62±n/a nM |
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| Comments | PDSP_1798 |
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| Citation |  Schwinn, DA; Johnston, GI; Page, SO; Mosley, MJ; Wilson, KH; Worman, NP; Campbell, S; Fidock, MD; Furness, LM; Parry-Smith, DJ Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. J Pharmacol Exp Ther272:134-42 (1995) [PubMed] |
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| More Info.: | Get all data from this article |
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| Solute carrier family 22 member 1 |
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| Name: | Solute carrier family 22 member 1 |
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| Synonyms: | OCT1 | S22A1_BOVIN | SLC22A1 | adrenergic Alpha1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 62499.05 |
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| Organism: | BOVINE |
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| Description: | adrenergic Alpha1 0 BOVINE::A7MBE0 |
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| Residue: | 563 |
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| Sequence: | MLTVDDVLEQVGEFGWFQKQTFLILCLLSAAFAPIYVGIVFLAFTPDHRCRSPGVAELSR
RCGWSLAEELNYTVPGPGPESQCLRYEVDWNQSTLGCLDPLASLATNGSPLPLGPCEQGW
VYDTPGSSIVTEFNLVCDDSWKVDLFQSCVNLGFFLGSLGVGYIADRFGRKVCLLATTLT
CASLGVLTAVAPDYTSLLIFRLLQGLVSKGSWTAGYTLITEFVGLGYRRTVAILYQMAFT
VGLVLLSGLAYILPHWRWLQLAVSLPIFLLLFRFWFVPESPRWLLSQKRNTEAIKIMDHI
AQKNGKLPPADLKMLSLEEDVTEKLSPSFIDLFRTPNLRKYTFILMYLWFTSSVVYQGLI
MHVGATGGNLYLDFLYSALVEFPAGFIILVTIDRFGRRYPLATSNLAAGLACFLMIFIPH
DLPWLNIMVACVGRMGITIVFQMVCLVNAELFPTFIRNLGMMVCSSLCDLGGVLTPFLVF
RLMEVWQGSPLILFAALGLVAGGMTLLLPETKGVTLPETIEDAENLQRKAKPKENKIYLQ
VQTSELNTQAAERDASQGTAQQK
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| BDBM50033111 |
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| n/a |
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| Name | BDBM50033111 |
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| Synonyms: | 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine | 6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine | CHEMBL611 | TERAZOSIN | Terazosine |
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| Type | Small organic molecule |
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| Emp. Form. | C19H25N5O4 |
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| Mol. Mass. | 387.4329 |
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| SMILES | COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1 |
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| Structure | 
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