Reaction Details |
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Target | 5-hydroxytryptamine receptor 3A |
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Ligand | BDBM82474 |
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Substrate/Competitor | n/a |
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Ki | 0.94±n/a nM |
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Comments | PDSP_3690 |
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Citation | Green, T; Stauffer, KA; Lummis, SC Expression of recombinant homo-oligomeric 5-hydroxytryptamine3 receptors provides new insights into their maturation and structure. J Biol Chem270:6056-61 (1995) [PubMed] Article |
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More Info.: | Get all data from this article |
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5-hydroxytryptamine receptor 3A |
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Name: | 5-hydroxytryptamine receptor 3A |
Synonyms: | 5-HT-3 | 5-HT3-A | 5-HT3A | 5-HT3A Serotonin Receptor | 5-HT3R | 5-hydroxytryptamine receptor 3 | 5-hydroxytryptamine receptor 3A | 5HT3A_MOUSE | 5ht3 | Htr3 | Htr3a | Serotonin 3 receptor (5HT3) | Serotonin 3a (5-HT3a) receptor | Serotonin receptor 3A | Serotonin-gated ion channel receptor |
Type: | n/a |
Mol. Mass.: | 56056.00 |
Organism: | Mus musculus (house mouse) |
Description: | 5HT3A |
Residue: | 487 |
Sequence: | MRLCIPQVLLALFLSMLTAPGEGSRRRATQEDTTQPALLRLSDHLLANYKKGVRPVRDWR
KPTTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFLQWTPEDFDNVTKLSIPTDSIW
VPDILINEFVDVGKSPNIPYVYVHHRGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFT
SWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELLEVFPQFKEFSIDISNSYAEMKFYV
IIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLP
ATIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQRPVPDWLRHLVLDRIAWILCL
GEQPMAHRPPATFQANKTDDCSGSDLLPAMGNHCSHVGGPQDLEKTPRGRGSPLPPPREA
SLAVRGLLQELSSIRHFLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTL
WSIWHYS
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BDBM82474 |
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n/a |
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Name | BDBM82474 |
Synonyms: | 1-(3-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE | CAS_2113-05-5 | m-chloro-phenyl-biguanide |
Type | Small organic molecule |
Emp. Form. | C8H10ClN5 |
Mol. Mass. | 211.652 |
SMILES | [#7]\[#6](-[#7])=[#7]\[#6](-[#7])=[#7]-c1cccc(Cl)c1 |w:6.6| |
Structure |
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