| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
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| Ligand | BDBM50013515 |
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| Substrate/Competitor | n/a |
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| Ki | 0.26±n/a nM |
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| Comments | PDSP_1590 |
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| Citation |  Bockman, CS; Jeffries, WB; Abel, PW Binding and functional characterization of alpha-2 adrenergic receptor subtypes on pig vascular endothelium. J Pharmacol Exp Ther267:1126-33 (1993) [PubMed] |
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| More Info.: | Get all data from this article |
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| Alpha-2A adrenergic receptor |
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| Name: | Alpha-2A adrenergic receptor |
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| Synonyms: | Alpha-2A adrenergic receptor | adrenergic Alpha2 | adrenergic Alpha2A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 48998.96 |
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| Organism: | PIG |
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| Description: | adrenergic Alpha2 0 PIG::P18871 |
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| Residue: | 450 |
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| Sequence: | MGSLQPEAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKAGGGG
QQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAAA
ALPGGAERRPNGLGPERGVGRVGAEAEPLPVQLNGAPGEPAPAGPRDADGLDLEESSSSE
HAERPPGPRRSERGPRAKSKARASQVKPGDSLPRRGPGAPGPGAPATGAGEERGGVAKAS
RWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPPTLFKFFFWFGYCNSS
LNPVIYTIFNHDFRRAFKKILCRGDRKRIV
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| BDBM50013515 |
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| n/a |
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| Name | BDBM50013515 |
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| Synonyms: | (+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester | 17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester | CHEMBL15245 | CORYNANTHINE | Johimbin | Quebrachin | RAUWOLSCINE | YOHIMBINE CHLORIDE | Yohimbin | Yohimbine | aphrodine | cid_8969 | corynine | methyl 17alpha-hydroxyyohimban-16alpha-carboxylate | quebrachine | yohimbic acid methyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26N2O3 |
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| Mol. Mass. | 354.4427 |
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| SMILES | COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| |
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| Structure | 
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