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TargetBeta-1 adrenergic receptor
LigandBDBM50019443
Substrate/Competitorn/a
Ki 1.94±n/a nM
CommentsPDSP_1495
Citation Fraundorfer, PF; Fertel, RH; Miller, DD; Feller, DR Biochemical and pharmacological characterization of high-affinity trimetoquinol analogs on guinea pig and human beta adrenergic receptor subtypes: evidence for partial agonism. J Pharmacol Exp Ther270:665-74 (1994) [PubMed]
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Beta-1 adrenergic receptor
Name:Beta-1 adrenergic receptor
Synonyms:ADRB1 | ADRB1R | ADRB1_HUMAN | B1AR | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:51338.40
Organism:Homo sapiens (Human)
Description:P08588
Residue:477
Sequence:
MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQGLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
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  Blast E-value cutoff:
BDBM50019443
n/a
NameBDBM50019443
Synonyms:1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol | 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol((-)-Pindolol) | 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol(pindolol) | 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol | LB-46 | PINDOLOL | PINDOLOL,(-) | PRINODOLOL | VISKAZIDE | VISKEN
TypeSmall organic molecule
Emp. Form.C14H20N2O2
Mol. Mass.248.3208
SMILESCC(C)NCC(O)COc1cccc2[nH]ccc12
Structure
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