Reaction Details | |||
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Target | Gastrin/cholecystokinin type B receptor | ||
Ligand | BDBM50040671 | ||
Substrate/Competitor | n/a | ||
Ki | 1600±n/a nM | ||
Comments | PDSP_2244 | ||
Citation | Patel, S; Smith, AJ; Chapman, KL; Fletcher, AE; Kemp, JA; Marshall, GR; Hargreaves, RJ; Ryecroft, W; Iversen, LL; Iversen, SD Biological properties of the benzodiazepine amidine derivative L-740,093, a cholecystokinin-B/gastrin receptor antagonist with high affinity in vitro and high potency in vivo. Mol Pharmacol46:943-8 (1994) [PubMed] | ||
More Info.: | Get all data from this article | ||
Gastrin/cholecystokinin type B receptor | |||
Name: | Gastrin/cholecystokinin type B receptor | ||
Synonyms: | Cckbr | Cholecystokinin A | Cholecystokinin B receptor | Cholecystokinin receptor | GASR_RAT | Gastrin/cholecystokinin type B receptor | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 48980.43 | ||
Organism: | RAT | ||
Description: | Cholecystokinin A CCKBR RAT::P30553 | ||
Residue: | 452 | ||
Sequence: |
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BDBM50040671 | |||
n/a | |||
Name | BDBM50040671 | ||
Synonyms: | 1-[5-(3-Aza-bicyclo[3.2.2]non-3-yl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-m-tolyl-urea | CHEMBL349291 | L-740,093 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H31N5O2 | ||
Mol. Mass. | 445.5566 | ||
SMILES | CN1c2ccccc2C(=NC(NC(=O)Nc2cccc(C)c2)C1=O)N1CC2CCC(CC2)C1 |c:9,(7.22,-6.97,;7.67,-8.45,;6.69,-9.39,;5.36,-8.63,;4.02,-9.39,;4.02,-10.93,;5.36,-11.69,;6.71,-10.96,;7.63,-11.85,;9.14,-11.6,;9.86,-10.19,;11.4,-10.21,;12.13,-11.53,;11.35,-12.86,;13.67,-11.57,;14.48,-10.26,;13.72,-8.91,;14.5,-7.6,;16.04,-7.62,;16.81,-8.95,;18.33,-8.98,;16.01,-10.29,;9.18,-8.72,;10.1,-7.49,;7.17,-13.34,;5.55,-13.5,;4.73,-14.54,;5.14,-16.05,;6.65,-16.64,;8.09,-15.8,;7.22,-14.74,;6.1,-14.2,;8.22,-14.23,)| | ||
Structure |