| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2B adrenergic receptor |
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| Ligand | BDBM81444 |
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| Substrate/Competitor | n/a |
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| Ki | 78±n/a nM |
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| Comments | PDSP_1955 |
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| Citation |  Uhlén, S; Porter, AC; Neubig, RR The novel alpha-2 adrenergic radioligand [3H]-MK912 is alpha-2C selective among human alpha-2A, alpha-2B and alpha-2C adrenoceptors. J Pharmacol Exp Ther271:1558-65 (1994) [PubMed] |
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| More Info.: | Get all data from this article |
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| Alpha-2B adrenergic receptor |
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| Name: | Alpha-2B adrenergic receptor |
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| Synonyms: | ADA2B_HUMAN | ADRA2B | ADRA2L1 | ADRA2RL1 | Adrenergic alpha2B | Adrenergic receptor | Adrenergic receptor alpha | Adrenergic, alpha-2B-, receptor [Homo sapiens] | Alpha-2 adrenergic receptor subtype C2 | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | Alpha-2BAR |
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| Type: | Enzyme |
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| Mol. Mass.: | 49964.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P18089 |
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| Residue: | 450 |
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| Sequence: | MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRR
AQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSS
LNPVIYTIFNQDFRRAFRRILCRPWTQTAW
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| BDBM81444 |
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| n/a |
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| Name | BDBM81444 |
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| Synonyms: | CAS_185453 | NSC_185453 | WB 4101 | WB-4101 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27NO5 |
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| Mol. Mass. | 421.4856 |
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| SMILES | COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1 |
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| Structure | 
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