Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetAdenosine receptor A2a
LigandBDBM82521
Substrate/Competitorn/a
Ki>10000±n/a nM
CommentsPDSP_2577
Citation van Galen, PJvan Bergen, AHGallo-Rodriguez, CMelman, NOlah, MEIJzerman, APStiles, GLJacobson, KA A binding site model and structure-activity relationships for the rat A3 adenosine receptor. Mol Pharmacol45:1101-11 (1994) [PubMed]
More Info.:Get all data from this article
 
Adenosine receptor A2a
Name:Adenosine receptor A2a
Synonyms:AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:45015.65
Organism:Rattus norvegicus (rat)
Description:Rat A2A receptors expressed in CHO cells.
Residue:410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKG
IIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAF
VLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALC
WLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRT
HVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGL
GGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM82521
n/a
NameBDBM82521
Synonyms:3,9-DimethylX | 3,9-Dimethylxanthine | 3,9-dimethyl-3,9-dihydro-1h-purine-2,6-dione
TypeSmall organic molecule
Emp. Form.C7H8N4O2
Mol. Mass.180.164
SMILESCn1cnc2c1n(C)c(=O)[nH]c2=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: