Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Muscarinic acetylcholine receptor M4 | ||
| Ligand | BDBM28347 | ||
| Substrate/Competitor | n/a | ||
| Ki | 11.1±n/a nM | ||
| Comments | PDSP_1203 | ||
| Citation |  Stanton, T; Bolden-Watson, C; Cusack, B; Richelson, E Antagonism of the five cloned human muscarinic cholinergic receptors expressed in CHO-K1 cells by antidepressants and antihistaminics. Biochem Pharmacol45:2352-4 (1993) [PubMed] Article | ||
| More Info.: | Get all data from this article | ||
| Muscarinic acetylcholine receptor M4 | |||
| Name: | Muscarinic acetylcholine receptor M4 | ||
| Synonyms: | ACM4_HUMAN | CHRM4 | Cholinergic, muscarinic M4 | Muscarinic acetylcholine receptor | Muscarinic acetylcholine receptor M2 and M4 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 53079.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Cholinergic, muscarinic M4 CHRM4 HUMAN M3::P08173 | ||
| Residue: | 479 | ||
| Sequence: |
| ||
| BDBM28347 | |||
| n/a | |||
| Name | BDBM28347 | ||
| Synonyms: | 3-(10H-phenothiazin-10-ylmethyl)-1-azabicyclo[2.2.2]octan-1-ium | Mequitazine | ZINC01567421, 6 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H23N2S | ||
| Mol. Mass. | 323.474 | ||
| SMILES | C(C1C[NH+]2CCC1CC2)N1c2ccccc2Sc2ccccc12 |THB:0:1:5.4:7.8,(14.51,-5.48,;15.79,-4.74,;17.21,-5.13,;17.6,-2.22,;20.16,-.74,;19.42,.54,;16.17,-1.84,;14.72,-.36,;16,.37,;14.51,-6.96,;15.79,-7.7,;17.11,-6.91,;18.45,-7.67,;18.45,-9.21,;17.11,-9.97,;15.79,-9.18,;14.51,-9.92,;13.22,-9.18,;11.9,-9.97,;10.56,-9.21,;10.56,-7.67,;11.9,-6.91,;13.22,-7.7,)| | ||
| Structure | 
| ||