Reaction Details |
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Target | Transmembrane and immunoglobulin domain-containing 3 |
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Ligand | BDBM21220 |
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Substrate/Competitor | n/a |
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Ki | 260.5±n/a nM |
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Comments | PDSP_1302 |
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Citation | Olah, ME; Gallo-Rodriguez, C; Jacobson, KA; Stiles, GL 125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor. Mol Pharmacol45:978-82 (1994) [PubMed] |
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More Info.: | Get all data from this article |
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Transmembrane and immunoglobulin domain-containing 3 |
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Name: | Transmembrane and immunoglobulin domain-containing 3 |
Synonyms: | ADENOSINE A3 | ADORA3 | Adora3 protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25707.75 |
Organism: | RAT |
Description: | Q4V8H0 |
Residue: | 232 |
Sequence: | MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNII
AFTPNSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNRED
RANGLSPGTSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQR
NRGVTGKSINRNPQASQAPSMVSIPLTVLPKVPRQNGQQKALQWTGNATKTG
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BDBM21220 |
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n/a |
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Name | BDBM21220 |
Synonyms: | (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide | Adenosine analog, 3 | Adenosine, N6-Ethyl-carboxamido | Adenosine-5-(N-ethylcarboxamide) | CHEMBL464859 | N-Ethylcarboxamidoadenosine | NECA |
Type | Antineoplastic Agent |
Emp. Form. | C12H16N6O4 |
Mol. Mass. | 308.2932 |
SMILES | CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |
Structure |
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