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TargetTransmembrane and immunoglobulin domain-containing 3
LigandBDBM21220
Substrate/Competitorn/a
Ki 260.5±n/a nM
CommentsPDSP_1302
Citation Olah, MEGallo-Rodriguez, CJacobson, KAStiles, GL 125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor. Mol Pharmacol45:978-82 (1994) [PubMed]
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Transmembrane and immunoglobulin domain-containing 3
Name:Transmembrane and immunoglobulin domain-containing 3
Synonyms:ADENOSINE A3 | ADORA3 | Adora3 protein
Type:Enzyme Catalytic Domain
Mol. Mass.:25707.75
Organism:RAT
Description:Q4V8H0
Residue:232
Sequence:
MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNII
AFTPNSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNRED
RANGLSPGTSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQR
NRGVTGKSINRNPQASQAPSMVSIPLTVLPKVPRQNGQQKALQWTGNATKTG
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BDBM21220
n/a
NameBDBM21220
Synonyms:(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide | Adenosine analog, 3 | Adenosine, N6-Ethyl-carboxamido | Adenosine-5-(N-ethylcarboxamide) | CHEMBL464859 | N-Ethylcarboxamidoadenosine | NECA
TypeAntineoplastic Agent
Emp. Form.C12H16N6O4
Mol. Mass.308.2932
SMILESCCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Structure
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