| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 5B |
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| Ligand | BDBM78940 |
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| Substrate/Competitor | n/a |
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| Ki | 44.2±n/a nM |
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| Comments | PDSP_1219 |
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| Citation |  Wisden, W; Parker, EM; Mahle, CD; Grisel, DA; Nowak, HP; Yocca, FD; Felder, CC; Seeburg, PH; Voigt, MM Cloning and characterization of the rat 5-HT5B receptor. Evidence that the 5-HT5B receptor couples to a G protein in mammalian cell membranes. FEBS Lett333:25-31 (1993) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 5B |
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| Name: | 5-hydroxytryptamine receptor 5B |
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| Synonyms: | 5-HT5B | 5-hydroxytryptamine receptor 5B | 5HT5B_RAT | 5ht5b | Htr5b | Serotonin (5-HT) receptor | Serotonin 5b (5-HT5b) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41141.95 |
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| Organism: | RAT |
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| Description: | 5-HT5B 0 RAT::P35365 |
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| Residue: | 370 |
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| Sequence: | MEVSNLSGATPGIAFPPGPESCSDSPSSGRSMGSTPGGLILSGREPPFSAFTVLVVTLLV
LLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSAGRRW
QLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRRRASALMIAITWA
LSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYVPLAVVLFVYWKIYKAA
KFRFGRRRRAVVPLPATTQAKEAPQESETVFTARCRATVAFQTSGDSWREQKEKRAAMMV
GILIGVFVLCWIPFFLTELVSPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNN
AFKSLFTKQR
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| BDBM78940 |
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| n/a |
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| Name | BDBM78940 |
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| Synonyms: | METHIOTHEPIN | MLS000859918 | Methiothepin mesylate salt | SMR000326779 | cid_3039995 | mesylic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine | methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine | methanesulfonic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2S2 |
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| Mol. Mass. | 356.548 |
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| SMILES | CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1 |
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| Structure | 
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