| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 3A |
|---|
| Ligand | BDBM50007892 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 6310±n/a nM |
|---|
| Comments | PDSP_621 |
|---|
| Citation |  Bonhaus, DW; Loury, DN; Jakeman, LB; To, Z; DeSouza, A; Eglen, RM; Wong, EH [3H]BIMU-1, a 5-hydroxytryptamine3 receptor ligand in NG-108 cells, selectively labels sigma-2 binding sites in guinea pig hippocampus. J Pharmacol Exp Ther267:961-70 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| 5-hydroxytryptamine receptor 3A |
|---|
| Name: | 5-hydroxytryptamine receptor 3A |
|---|
| Synonyms: | 5-HT3 | 5-hydroxytryptamine receptor 3A | 5HT3A_CAVPO | 5HT3R | HTR3 | HTR3A | Serotonin 3a (5-HT3a) receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 55657.07 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | 5-HT3 HTR3A GUINEA PIG::O70212 |
|---|
| Residue: | 490 |
|---|
| Sequence: | MVLWLQLALLALLLPTSLAQGEVRGKGTAQAHNSTRPALQRLSDHLLADYRKSVRPVRDW
RKPTTVSIDAIVYAILSVDEKNQVLTTYIWYRQFWTDEFLQWNPEDFDNITKLSIPTDSI
WVPDILINEFVDVGKSPNIPYVYVRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTF
TSWLHTIQDINISLWRLPEKVKSDKSVFMNQGEWELLGVLTEFLEFSDRESRGSFAEMKF
YVVIRRRPLFYAVTLLLPSIFLMIVDIVGFYLPPDSGERVSFKITLLLGYSVFLIIVSDT
LPATAIGTPLISVYFVVCMALLVISLAETILIVRLVHKQDLQQPVPLWLRHLVLERIAGL
LCLGEQLTSHRGPATLQATKTDDFSGSTLLPAMGNHCGPLGGPQDLEKTSRGRGSPPPPP
REASLAMCGLLQELASIRHFLEKREETREVARDWLRVGSVLDKLLFRVYLLAVLAYSITL
VTLWSVWHYA
|
|
|
|---|
| BDBM50007892 |
|---|
| n/a |
|---|
| Name | BDBM50007892 |
|---|
| Synonyms: | 2-Oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide; hydrochloride | CHEMBL539261 | DAU 6215 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H20N4O2 |
|---|
| Mol. Mass. | 300.3556 |
|---|
| SMILES | CN1C2CCC1CC(C2)NC(=O)n1c2ccccc2[nH]c1=O |TLB:9:7:1:3.4| |
|---|
| Structure | 
|
|---|
Search and Browse
