Ki Summary

Reaction Details

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Target

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Ligand

BDBM33116

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay

IC50

5891±296 nM

Citation

PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Assay Method

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Name:

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

29199.89

Organism:

Homo sapiens (Human)

Description:

gi_10864009

Residue:

261

Sequence:

MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGA
PLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEI
DGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRES
CVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPF
FEQLSRVDDVYSVLRQPRPGS

BDBM33116

n/a

Name

BDBM33116

Synonyms:

(E)-3-(5-methyl-2-furanyl)-N-[3-[[(E)-3-(5-methyl-2-furanyl)-1-oxoprop-2-enyl]amino]-4-nitrophenyl]-2-propenamide | (E)-3-(5-methyl-2-furyl)-N-[3-[[(E)-3-(5-methyl-2-furyl)acryloyl]amino]-4-nitro-phenyl]acrylamide | (E)-3-(5-methylfuran-2-yl)-N-[3-[[(E)-3-(5-methylfuran-2-yl)prop-2-enoyl]amino]-4-nitro-phenyl]prop-2-enamide | (E)-3-(5-methylfuran-2-yl)-N-[3-[[(E)-3-(5-methylfuran-2-yl)prop-2-enoyl]amino]-4-nitrophenyl]prop-2-enamide | MLS000578867 | N,N'-(4-nitro-1,3-phenylene)bis[3-(5-methyl-2-furyl)acrylamide] | SMR000197853 | cid_5736971

Type

Small organic molecule

Emp. Form.

C22H19N3O6

Mol. Mass.

421.4028

SMILES

Cc1ccc(\C=C\C(=O)Nc2ccc(c(NC(=O)\C=C\c3ccc(C)o3)c2)[N+]([O-])=O)o1

Structure