Ki Summary

Reaction Details

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Target

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Ligand

BDBM48851

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay

IC50

2957±115 nM

Citation

PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Assay Method

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Name:

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

Synonyms:

Type:

Enzyme Catalytic Domain

Mol. Mass.:

29199.89

Organism:

Homo sapiens (Human)

Description:

gi_10864009

Residue:

261

Sequence:

MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGA
PLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEI
DGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRES
CVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPF
FEQLSRVDDVYSVLRQPRPGS

BDBM48851

n/a

Name

BDBM48851

Synonyms:

2-[6-(2-fluorobenzyl)-4-keto-5,7-dimethyl-pyrrolo[3,4-d]pyridazin-3-yl]-N-(2,3,5,6-tetrafluorophenyl)acetamide | 2-[6-(2-fluorobenzyl)-5,7-dimethyl-1-oxo-1,6-dihydro-2H-pyrrolo[3,4-d]pyridazin-2-yl]-N-(2,3,5,6-tetrafluorophenyl)acetamide | 2-[6-[(2-fluorophenyl)methyl]-5,7-dimethyl-4-oxidanylidene-pyrrolo[3,4-d]pyridazin-3-yl]-N-[2,3,5,6-tetrakis(fluoranyl)phenyl]ethanamide | 2-[6-[(2-fluorophenyl)methyl]-5,7-dimethyl-4-oxo-3-pyrrolo[3,4-d]pyridazinyl]-N-(2,3,5,6-tetrafluorophenyl)acetamide | 2-[6-[(2-fluorophenyl)methyl]-5,7-dimethyl-4-oxopyrrolo[3,4-d]pyridazin-3-yl]-N-(2,3,5,6-tetrafluorophenyl)acetamide | MLS000660595 | SMR000310114 | cid_16194171

Type

Small organic molecule

Emp. Form.

C23H17F5N4O2

Mol. Mass.

476.3987

SMILES

Cc1n(Cc2ccccc2F)c(C)c2c1cnn(CC(=O)Nc1c(F)c(F)cc(F)c1F)c2=O

Structure