| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
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| Ligand | BDBM83003 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay |
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| IC50 | 3151±415 nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
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| Name: | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
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| Synonyms: | CTDS1_HUMAN | CTDSP1 | NIF3 | NLIIF | SCP1 | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 29199.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_10864009 |
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| Residue: | 261 |
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| Sequence: | MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGA
PLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEI
DGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRES
CVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPF
FEQLSRVDDVYSVLRQPRPGS
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| BDBM83003 |
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| n/a |
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| Name | BDBM83003 |
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| Synonyms: | (6E)-5-azanylidene-6-[[3-methoxy-4-[2-(4-methylphenoxy)ethoxy]phenyl]methylidene]-2-methylsulfonyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one | (6E)-5-imino-2-mesyl-6-[3-methoxy-4-[2-(4-methylphenoxy)ethoxy]benzylidene]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one | (6E)-5-imino-6-[[3-methoxy-4-[2-(4-methylphenoxy)ethoxy]phenyl]methylidene]-2-methylsulfonyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one | (6E)-5-imino-6-{3-methoxy-4-[2-(4-methylphenoxy)ethoxy]benzylidene}-2-(methylsulfonyl)-5,6-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one | MLS001199626 | SMR000560211 | cid_24792310 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22N4O6S2 |
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| Mol. Mass. | 514.574 |
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| SMILES | COc1cc(C=C2C(=O)N=C3SC(=NN3C2=N)S(C)(=O)=O)ccc1OCCOc1ccc(C)cc1 |w:5.4,c:12,t:9| |
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| Structure | 
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