| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 6 |
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| Ligand | BDBM54506 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay |
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| IC50 | 16700±n/a nM |
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| Citation |  PubChem, PC SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 6 |
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| Name: | C-C chemokine receptor type 6 |
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| Synonyms: | C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42510.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51684 |
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| Residue: | 374 |
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| Sequence: | MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM
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| BDBM54506 |
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| n/a |
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| Name | BDBM54506 |
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| Synonyms: | 5-chloranyl-N-(4-fluorophenyl)-2-[(2-methylphenyl)methylsulfonyl]pyrimidine-4-carboxamide | 5-chloro-N-(4-fluorophenyl)-2-(2-methylbenzyl)sulfonyl-pyrimidine-4-carboxamide | 5-chloro-N-(4-fluorophenyl)-2-[(2-methylphenyl)methylsulfonyl]-4-pyrimidinecarboxamide | 5-chloro-N-(4-fluorophenyl)-2-[(2-methylphenyl)methylsulfonyl]pyrimidine-4-carboxamide | MLS001116168 | SMR000625791 | cid_16452954 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H15ClFN3O3S |
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| Mol. Mass. | 419.857 |
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| SMILES | Cc1ccccc1CS(=O)(=O)c1ncc(Cl)c(n1)C(=O)Nc1ccc(F)cc1 |
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| Structure | 
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