Reaction Details |
| Report a problem with these data |
Target | C-C chemokine receptor type 6 |
---|
Ligand | BDBM54428 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay |
---|
IC50 | 10400±n/a nM |
---|
Citation | PubChem, PC SAR analysis of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay(2011)[AID] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
C-C chemokine receptor type 6 |
---|
Name: | C-C chemokine receptor type 6 |
Synonyms: | C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22 |
Type: | Enzyme |
Mol. Mass.: | 42510.84 |
Organism: | Homo sapiens (Human) |
Description: | P51684 |
Residue: | 374 |
Sequence: | MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM
|
|
|
BDBM54428 |
---|
n/a |
---|
Name | BDBM54428 |
Synonyms: | 2-(4-methylphenyl)sulfonyl-5-nitro-pyridine | 2-(4-methylphenyl)sulfonyl-5-nitropyridine | 4-methylphenyl 5-nitro-2-pyridinyl sulfone | 5-nitro-2-tosyl-pyridine | MLS001165624 | SMR000550074 | cid_1472329 |
Type | Small organic molecule |
Emp. Form. | C12H10N2O4S |
Mol. Mass. | 278.284 |
SMILES | Cc1ccc(cc1)S(=O)(=O)c1ccc(cn1)[N+]([O-])=O |
Structure |
|