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Reaction Details
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TargetPhospholipase A2
LigandBDBM80075
Substrate/Competitorn/a
Meas. Tech.Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50>80000±n/a nM
Citation PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,  Assay Method
 
Phospholipase A2
Name:Phospholipase A2
Synonyms:Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:Protein
Mol. Mass.:16364.13
Organism:Homo sapiens (Human)
Description:P04054
Residue:148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV
DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC
DRNAAICFSKAPYNKAHKNLDTKKYCQS
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  Blast E-value cutoff:
BDBM80075
n/a
NameBDBM80075
Synonyms:7-bromanyl-6-methoxy-quinoline-5,8-dione | 7-bromo-6-methoxy-quinoline-5,8-quinone | 7-bromo-6-methoxyquinoline-5,8-dione | MLS002703741 | SMR001570458 | cid_265935
TypeSmall organic molecule
Emp. Form.C10H6BrNO3
Mol. Mass.268.064
SMILESCOC1=C(Br)C(=O)c2ncccc2C1=O |c:2|
Structure
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