Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM83319 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay |
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EC50 | >92480±n/a nM |
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Citation | PubChem, PC Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM83319 |
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n/a |
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Name | BDBM83319 |
Synonyms: | 1-[2-(dimethylamino)-2-(3-pyridinyl)ethyl]-3-(3-methylphenyl)thiourea | 1-[2-(dimethylamino)-2-(3-pyridyl)ethyl]-3-(m-tolyl)thiourea | 1-[2-(dimethylamino)-2-pyridin-3-yl-ethyl]-3-(3-methylphenyl)thiourea | 1-[2-(dimethylamino)-2-pyridin-3-ylethyl]-3-(3-methylphenyl)thiourea | MLS000720335 | SMR000236204 | cid_3600177 |
Type | Small organic molecule |
Emp. Form. | C17H22N4S |
Mol. Mass. | 314.448 |
SMILES | CN(C)C(CNC(=S)Nc1cccc(C)c1)c1cccnc1 |
Structure |
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