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TargetDelta-type opioid receptor
LigandBDBM83319
Substrate/Competitorn/a
Meas. Tech.Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay
EC50>92480±n/a nM
Citation PubChem, PC Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Delta-type opioid receptor
Synonyms:D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40382.98
Organism:Homo sapiens (Human)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM83319
n/a
NameBDBM83319
Synonyms:1-[2-(dimethylamino)-2-(3-pyridinyl)ethyl]-3-(3-methylphenyl)thiourea | 1-[2-(dimethylamino)-2-(3-pyridyl)ethyl]-3-(m-tolyl)thiourea | 1-[2-(dimethylamino)-2-pyridin-3-yl-ethyl]-3-(3-methylphenyl)thiourea | 1-[2-(dimethylamino)-2-pyridin-3-ylethyl]-3-(3-methylphenyl)thiourea | MLS000720335 | SMR000236204 | cid_3600177
TypeSmall organic molecule
Emp. Form.C17H22N4S
Mol. Mass.314.448
SMILESCN(C)C(CNC(=S)Nc1cccc(C)c1)c1cccnc1
Structure
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