| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM68066 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay |
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| EC50 | >92498±n/a nM |
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| Citation |  PubChem, PC Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM68066 |
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| n/a |
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| Name | BDBM68066 |
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| Synonyms: | 1-(4-fluorophenyl)-N-[2-hydroxy-5-[(4-methoxyphenyl)sulfamoyl]phenyl]-3-methyl-5-thieno[2,3-c]pyrazolecarboxamide | 1-(4-fluorophenyl)-N-[2-hydroxy-5-[(4-methoxyphenyl)sulfamoyl]phenyl]-3-methyl-thieno[2,3-c]pyrazole-5-carboxamide | 1-(4-fluorophenyl)-N-[2-hydroxy-5-[(4-methoxyphenyl)sulfamoyl]phenyl]-3-methylthieno[2,3-c]pyrazole-5-carboxamide | 1-(4-fluorophenyl)-N-[5-[(4-methoxyphenyl)sulfamoyl]-2-oxidanyl-phenyl]-3-methyl-thieno[2,3-c]pyrazole-5-carboxamide | MLS000401592 | SMR000243497 | cid_3690550 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H21FN4O5S2 |
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| Mol. Mass. | 552.597 |
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| SMILES | COc1ccc(NS(=O)(=O)c2ccc(O)c(NC(=O)c3cc4c(C)nn(-c5ccc(F)cc5)c4s3)c2)cc1 |
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| Structure | 
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