Reaction Details |
| Report a problem with these data |
Target | Delta-type opioid receptor |
---|
Ligand | BDBM83365 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay |
---|
EC50 | >92450±n/a nM |
---|
Citation | PubChem, PC Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization PubChem Bioassay(2011)[AID] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Delta-type opioid receptor |
---|
Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
|
|
|
BDBM83365 |
---|
n/a |
---|
Name | BDBM83365 |
Synonyms: | 4-chloranyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-N-(2-phenylethyl)benzamide;hydrochloride | 4-chloro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-N-(2-phenylethyl)benzamide;hydrochloride | 4-chloro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-N-phenethyl-benzamide;hydrochloride | MLS000712245 | SMR000282012 | cid_2862001 |
Type | Small organic molecule |
Emp. Form. | C23H25ClN2O |
Mol. Mass. | 380.91 |
SMILES | [H]C12CCC([H])(C=C(C1)N(CCc1ccccc1)C(=O)c1ccc(Cl)cc1)N2C |c:6| |
Structure |
|