Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM83391 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay |
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EC50 | >92439±n/a nM |
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Citation | PubChem, PC Counterscreen for agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors: Luminescence-based cell-based high throughput dose response assay to identify agonists of OPRD1 homodimerization PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40382.98 |
Organism: | Homo sapiens (Human) |
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
Residue: | 372 |
Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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BDBM83391 |
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n/a |
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Name | BDBM83391 |
Synonyms: | (1S,4aS,8aS)-7-[2-(1H-indol-3-yl)ethyl]-1-methyl-1,4a,5,6,8,8a-hexahydropyrano[3,4-c]pyridine-4-carboxylic acid methyl ester | MLS000728582 | SMR000470773 | cid_23641069 | methyl (1S,4aS,8aS)-7-[2-(1H-indol-3-yl)ethyl]-1-methyl-1,4a,5,6,8,8a-hexahydropyrano[3,4-c]pyridine-4-carboxylate |
Type | Small organic molecule |
Emp. Form. | C21H26N2O3 |
Mol. Mass. | 354.4427 |
SMILES | COC(=O)C1=CO[C@@H](C)[C@@H]2CN(CCc3c[nH]c4ccccc34)CC[C@H]12 |t:4| |
Structure |
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